| Autor: |
Felipe Diaz-Toro, Gabriela Nazar, Claudia Troncoso, Yeny Concha-Cisternas, Ana Maria Leiva-Ordoñez, Maria Adela Martinez-Sanguinetti, Solange Parra-Soto, Nicole Lasserre-Laso, Igor Cigarroa, Lorena Mardones, Jaime Vásquez-Gómez, Fanny Petermann-Rocha, Ximena Diaz-Martinez, Carlos Celis-Morales |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
International Journal of Environmental Research and Public Health; Volume 20; Issue 2; Pages: 1195 |
| ISSN: |
1660-4601 |
| Popis: |
We aimed to investigate the association between frailty status and all-cause mortality in middle-aged and older people. We included 2661 individuals aged ≥ 35 from the Chilean National Health Survey 2009–2010. Mortality was determined through linkage with the Chilean Civil Registry and Identification. A 36-item frailty index (FI) was used to assess the frailty status. Associations between frailty status and all-cause mortality were assessed using Kaplan–Meier and Cox proportional hazard models adjusted for sociodemographic and lifestyle factors. A non-linear association was investigated using penalized cubic splines fitted in the Cox models. During an 8.9 median follow-up (interquartile range of 8.6–9.0), 308 individuals died (11.5%). Lower survival rates were observed in frail individuals compared to pre-frail and robust people (log-rank < 0.001). Compared with robust individuals, frail people had a higher mortality risk (HR: 2.35 [95% CI: 1.57 to 3.51]). Frail middle-aged individuals had a higher risk of dying independently of major risk factors. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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