Pregnancies in women with Turner syndrome: a retrospective multicentre UK study

Autor: Lucy MacKiliop, Catriona Bhagra, Lowri A. Allen, Aisling Carroll, Katherine von Klemperer, Fionnuala M. McAuliffe, R. Katie Morris, Paul Timmons, Catherine Head, Asha Shetty, Farah Siddiqui, Aidan P Bolger, D. Aled Rees, Matilde Calanchini, Claire Alexander, Philip J. Steer, Samantha Bonner, Linden Stocker, Rachael James, Dawn Adamson, Lydia Simpson, Eleanor Joy, Lucy Hudsmith, Niamh Keating, Sarah Vause, Mandeep K. Kaler, Helen E Turner, Ruth T Casey, Kate English, Aarthi R Mohan, Stephanie L. Curtis, Matthew Cauldwell
Rok vydání: 2022
Předmět:
Zdroj: BJOG: An International Journal of Obstetrics & Gynaecology. 129:796-803
ISSN: 1471-0528
1470-0328
DOI: 10.1111/1471-0528.17025
Popis: Objective\ud To determine the characteristics and outcomes of pregnancy in women with Turner Syndrome\ud \ud Design\ud Retrospective 20-year cohort study (2000-2020)\ud \ud Setting\ud 16 tertiary referral maternity units in the UK\ud \ud Population or Sample\ud 81 women with Turner syndrome who became pregnant\ud \ud Methods\ud Retrospective chart analysis\ud \ud Main Outcome Measures\ud Mode of conception, pregnancy outcomes\ud \ud Results\ud We obtained data on 127 pregnancies in 81 women with a Turner phenotype. All non-spontaneous pregnancies (54/127 (42.5%)) were by egg donation. Only 9/31 (29%) of pregnancies in women with karyotype 45,X were spontaneous, compared with 53/66 (80.3%) with mosaic karyotype 45,X/46,XX (p
Databáze: OpenAIRE
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