Age, Sex, and Depot‐Specific Differences in Adipose‐Tissue Estrogen Receptors in Individuals with Obesity
| Autor: | James Pitt, Nicole Spencer, Jillian Barnas, Jill A. Kanaley, Jay W. Porter, Rebecca J. Welly, Victoria J. Vieira-Potter |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Endocrinology Diabetes and Metabolism Medicine (miscellaneous) Adipose tissue Estrogen receptor 030209 endocrinology & metabolism White adipose tissue Article 03 medical and health sciences 0302 clinical medicine Endocrinology Internal medicine medicine Humans Obesity 030212 general & internal medicine Aromatase Aged Sex Characteristics Nutrition and Dietetics biology business.industry Age Factors Middle Aged medicine.disease Thermogenin Adipose Tissue Receptors Estrogen biology.protein Female business Estrogen receptor alpha Sex characteristics |
| Zdroj: | Obesity (Silver Spring) |
| ISSN: | 1930-739X 1930-7381 |
| DOI: | 10.1002/oby.22888 |
| Popis: | OBJECTIVE The aim of this study was to examine the effects of sex and menopausal status on depot-specific estrogen signaling in white adipose tissue (AT) in age-matched men and women with morbid obesity. METHODS A total of 28 premenopausal women, 16 postmenopausal women, and 27 age-matched men undergoing bariatric surgery were compared for omental (OM) AT (OMAT) and abdominal subcutaneous (SQ) AT (SQAT) genes and proteins. RESULTS With the exception of fasting nonesterified fatty acids being higher in women (P |
| Databáze: | OpenAIRE |
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