Relation of exercise capacity to left ventricular systolic function and diastolic filling in idiopathic or ischemic dilated cardiomyopathy
| Autor: | Annie Robert, Rigobert Lapu-Bula, Jean-Louis Vanoverschelde, Anne-Marie D'hondt, Jacques Melin, Martine De Kock, Jean-Marie R. Detry |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Cardiomyopathy Dilated Male medicine.medical_specialty Systole Rest Physical Exertion Cardiac Output Low Myocardial Ischemia Diastole Radionuclide ventriculography Exercise intolerance Ventricular Function Left Internal medicine Confidence Intervals Humans Medicine Cardiac Output Aged Analysis of Variance Exercise Tolerance Ejection fraction business.industry Mitral Valve Insufficiency VO2 max Gated Blood-Pool Imaging Stroke Volume Dilated cardiomyopathy Middle Aged medicine.disease Echocardiography Doppler Circadian Rhythm Echocardiography Heart failure Exercise Test Cardiology Regression Analysis medicine.symptom Cardiology and Cardiovascular Medicine business Blood Flow Velocity |
| Zdroj: | The American Journal of Cardiology. 83:728-734 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/s0002-9149(98)00979-5 |
| Popis: | Although exercise intolerance is a cardinal symptom of patients with dilated cardiomyopathy (DC) and heart failure, the factors that limit exercise capacity in these patients remain a matter of debate. To assess the contribution of left ventricular (LV) diastolic filling to the variable exercise capacity of patients with DC, we studied 47 patients (60 +/- 12 years) with DC in stable mild-to-moderate heart failure with a mean LV ejection fraction of 28%. Exercise capacity was measured as total body peak oxygen consumption (VO2) during symptom-limited bicycle (10 W/min) and treadmill (modified Bruce protocol) exercise. LV systolic function and diastolic filling were assessed at rest before each exercise by M-mode, Doppler echocardiography, and radionuclide ventriculography. As expected, treadmill exercise always yielded higher peak VO2 than bicycle exercise (21 +/- 6 vs 18 +/- 5 ml/kg/min, range 12 to 35 and 7 to 30 ml/kg/min, respectively, p |
| Databáze: | OpenAIRE |
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