Hemangiopericytoma in the Eyelid of a Horse
| Autor: | K. S. Joiner, A. Serena, J. Schumacher |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty 040301 veterinary sciences Vimentin Stain 0403 veterinary science 03 medical and health sciences medicine Animals Arabian horse Horses Hemangiopericytoma General Veterinary Glial fibrillary acidic protein biology Horse 04 agricultural and veterinary sciences Anatomy medicine.disease Immunohistochemistry 030104 developmental biology medicine.anatomical_structure Eyelid Diseases biology.protein Female Horse Diseases Eyelid |
| Zdroj: | Veterinary Pathology. 43:576-578 |
| ISSN: | 1544-2217 0300-9858 |
| DOI: | 10.1354/vp.43-4-576 |
| Popis: | Hemangiopericytoma (HP) is a well-recognized neoplasm arising from vascular pericytes that has been reported only in the dog and man. In this study, we describe a 14-year-old female Arabian horse that was presented for surgical excision of a 2-cm-diameter expansile subcuticular mass in the right lower eyelid. Histologically, the mass consisted of loosely arranged interlacing streams and storiform bundles of spindle cells that often formed distinct whorls around a central capillary and bundles of collagen (Antoni A-like pattern). Immunohistochemical analysis revealed strong diffuse cytoplasmic immunoreactivity for vimentin and focal immunoreactivity for smooth muscle actin, whereas neoplastic cells did not stain for Factor VIII-related antigen, Glial fibrillary acidic protein (GFAP), or S100. On the basis of histomorphology and immunohistochemical reactivity, the present tumor was diagnosed as HP. To our knowledge, this is the first report describing a HP in a horse. |
| Databáze: | OpenAIRE |
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