A Comparison of a Pulse-Based Diet and the Therapeutic Lifestyle Changes Diet in Combination with Exercise and Health Counselling on the Cardio-Metabolic Risk Profile in Women with Polycystic Ovary Syndrome: A Randomized Controlled Trial
| Autor: | Roger A. Pierson, Maryam Kazemi, Donna R. Chizen, Philip D. Chilibeck, Laura E. McBreairty, Gordon A. Zello |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Blood Glucose
Counseling medicine.medical_treatment physical activity Gastroenterology chemistry.chemical_compound 0302 clinical medicine Risk Factors Single-Blind Method glucose 030219 obstetrics & reproductive medicine Nutrition and Dietetics Area under the curve food and beverages Fabaceae respiratory system Polycystic ovary Lipids Cardiovascular Diseases pulse foods Female Lens Plant Therapeutic Lifestyle Changes lcsh:Nutrition. Foods and food supply Polycystic Ovary Syndrome Adult medicine.medical_specialty insulin lifestyle Adolescent lcsh:TX341-641 030209 endocrinology & metabolism Article metabolic syndrome 03 medical and health sciences Metabolic Diseases lipid Internal medicine medicine Aerobic exercise Humans Exercise Life Style Triglyceride business.industry Insulin medicine.disease Diet Blood pressure chemistry Glycemic Index Metabolic syndrome Insulin Resistance business dietary intake Food Science |
| Zdroj: | Nutrients Volume 10 Issue 10 Nutrients, Vol 10, Iss 10, p 1387 (2018) |
| ISSN: | 2072-6643 |
| Popis: | We compared the effects of a low-glycemic index pulse-based diet, containing lentils, beans, split peas, and chickpeas, to the Therapeutic Lifestyle Changes (TLC) diet on cardio-metabolic measures in women with polycystic ovary syndrome (PCOS). Ninety-five women (18&ndash 35 years) enrolled in a 16-week intervention 30 women in the pulse-based and 31 in the TLC groups completed the study. Women participated in aerobic exercise training (minimum 5 days/week for 45 min/day) and were counselled (monthly) about PCOS and lifestyle modification. Women underwent longitudinal follow-up post-intervention. The pulse-based group had a greater reduction in total area under the curve for insulin response to a 75-g oral glucose tolerance test (mean change ± SD: &minus 121.0 ± 229.9 vs. &minus 27.4 ± 110.2 µ IU/mL × min p = 0.05) diastolic blood pressure (&minus 3.6 ± 6.7 vs. &minus 0.2 ± 6.7 mmHg, p = 0.05) triglyceride (&minus 0.6 vs. 0.0 ± 0.5 mmol/L, p = 0.04) low-density lipoprotein cholesterol (&minus 0.4 vs. &minus 0.1 ± 0.4 mmol/L, p = 0.05) total cholesterol/high-density lipoprotein cholesterol (TC/HDL-C &minus 0.4 ± 0.4 vs. 0.1 ± 0.4, p < 0.001) and a greater increase in HDL-C (0.1 ± 0.2 vs. &minus 0.2 mmol/L, p < 0.01) than the TLC group. Decreased TC/HDL-C (p = 0.02) at six-month and increased HDL-C and decreased TC/HDL-C (p &le 0.02) at 12-month post-intervention were maintained in the pulse-based group. A pulse-based diet may be more effective than the TLC diet at improving cardio-metabolic disease risk factors in women with PCOS. Trial registration: CinicalTrials.gov identifier, NCT01288638. |
| Databáze: | OpenAIRE |
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