Therapeutic dilemmas in patient with perianal Crohn's disease and corticosteroid dependent difficult-to-control asthma
| Autor: | Marija Crnčević Urek, Milan Kujundžić, Marko Banić, Mirna Korica |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Pediatrics
medicine.medical_specialty Past medical history Allergy Crohn's disease corticosteroid dependent asthma business.industry Gastroenterology General Medicine medicine.disease respiratory tract diseases Surgery medicine Salbutamol Salmeterol Young adult business Montelukast Fluticasone medicine.drug Asthma |
| Popis: | Dear Sir, We present a 53 years old woman who suffered from endogenous difficult-to-control asthma from young adult age, with need of chronic use of oral corticosteroid therapy (metilprednisolone 16–24 mg/day > 50% year) together with treatment of high doses of inhaled corticosteroids and daily requirement of long acting beta 2 agonist. Despite therapy, asthma was poorly controlled with FEV1 20%. In the year 2008 perianal Crohn's disease was diagnosed in this patient. She had a history of asthma since young adult age that had been poorly controlled, with need of chronic use of oral corticosteroid therapy. She reported daily symptoms and almost nightly nocturnal awakenings due to shortness of breath, which were temporarily relieved with bronchodilators. She had had several exacerbations of asthma in the past 2 years requiring hospitalization. Her past medical history was negative for perennial allergies. She was a lifelong nonsmoker and denied any illicit drug use. Current pulmonary medication included: metilprednisolone 16–24 mg/day, fluticasone/salmeterol 500 ug/50 ug twice daily, montelukast 10 mg once daily and salbutamol on an as-needed basis which she was currently using three … |
| Databáze: | OpenAIRE |
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