Rhinovirus Viremia in Patients Hospitalized With Community-Acquired Pneumonia
| Autor: | Xiaoyan Lu, Chris Stockmann, Anami Patel, Kathryn M. Edwards, Dean D. Erdman, Carlos G. Grijalva, Eileen Schneider, Sandra R. Arnold, Seema Jain, Andrew T. Pavia, Wesley H. Self, Richard G. Wunderink, Evan J. Anderson, Weston Hymas, Anna M. Bramley, James D. Chappell, Derek J. Williams, Jonathan A. McCullers, Krow Ampofo |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Adolescent Rhinovirus Pneumonia Viral Viremia Real-Time Polymerase Chain Reaction medicine.disease_cause Article 03 medical and health sciences 0302 clinical medicine Community-acquired pneumonia Internal medicine medicine Humans Immunology and Allergy 030212 general & internal medicine Child Aged Subclinical infection Aged 80 and over Reactive airway disease Respiratory tract infections business.industry Middle Aged medicine.disease Community-Acquired Infections Pneumonia 030104 developmental biology Infectious Diseases medicine.anatomical_structure Child Preschool Female business Respiratory tract |
| Zdroj: | The Journal of Infectious Diseases. 216:1104-1111 |
| ISSN: | 1537-6613 0022-1899 |
| Popis: | Background Rhinoviruses (RVs) are ubiquitous respiratory pathogens that often cause mild or subclinical infections. Molecular detection of RVs from the upper respiratory tract can be prolonged, complicating etiologic association in persons with severe lower respiratory tract infections. Little is known about RV viremia and its value as a diagnostic indicator in persons hospitalized with community-acquired pneumonia (CAP). Methods Sera from RV-positive children and adults hospitalized with CAP were tested for RV by real-time reverse-transcription polymerase chain reaction. Rhinovirus species and type were determined by partial genome sequencing. Results Overall, 57 of 570 (10%) RV-positive patients were viremic, and all were children aged |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|