Results of oophorectomy by menstrual and estrogen receptor states in patients with metastatic breast cancer
| Autor: | William S. Fletcher, Alan E. Awrich, Michael E. Peetz, Edward J. Keenan, Charlene E. Davenport, H.Stephens Moseley |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Oncology
medicine.medical_specialty medicine.medical_treatment Estrogen receptor Breast Neoplasms Breast cancer Internal medicine medicine Carcinoma Endocrine system Humans Castration Gynecology business.industry Oophorectomy Cancer General Medicine medicine.disease Metastatic breast cancer Menstruation Menopause Receptors Estrogen Surgery Female business |
| Zdroj: | American journal of surgery. 141(5) |
| ISSN: | 0002-9610 |
| Popis: | The records of 204 women with metastatic breast carcinoma treated by oophorectomy were analyzed. Premenopausal women had a response rate of 50 percent. Forty-one percent of postmenopausal women responded. Those who responded had an average duration of response of 22 months and a length of survival twice that of the nonresponders. There was a better than 60 percent correlation between response to oophorectomy and response to further endocrine ablation. Response to endocrine manipulation is more a function of the hormonal sensitivity of the carcinoma than of menopausal status. |
| Databáze: | OpenAIRE |
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