Analysis of codon-specific translation by ribosome profiling

Autor:	Sebastian A. Leidel, Olga Sin, Leon Kleemann, Cristian Eggers, Yeji Kim, Ekaterina Shvetsova
Rok vydání:	2021
Předmět:	biology Chemistry 540 Chemistry Transfer RNA Saccharomyces cerevisiae RNA modification 570 Life sciences RNA Translation (biology) sense organs Ribosome profiling Computational biology biology.organism_classification
Zdroj:	Methods in Enzymology ISBN: 9780128235850
DOI:	10.1016/bs.mie.2021.06.025
Popis:	Chemical modifications of RNA molecules can affect translation in multiple ways. Therefore, it is critical to understand how their absence changes cellular translation dynamics and in particular codon-specific translation. In this chapter, we discuss the application of ribosome profiling to analyze changes in codon-specific translation and differential translation in Saccharomyces cerevisiae and human cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152ab891a3d62c73eef7c56d123b3b31 https://doi.org/10.1016/bs.mie.2021.06.025 Zobrazit plný text záznamu