Role of pregnancy hormones and hormonal interaction on the maternal cardiovascular system: a literature review
Autor: | Feriel Azibani, Karen Sliwa, Vitaris Kodogo |
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Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
Pregnancy Complications Cardiovascular Physiology Gestation period 030204 cardiovascular system & hematology Cardiovascular System road traffic crash 03 medical and health sciences 0302 clinical medicine Pregnancy Internal medicine medicine Humans 030212 general & internal medicine Permissive Progesterone Fetus Estradiol business.industry Hemodynamics General Medicine medicine.disease Prolactin quality of life Cardiovascular Diseases posttraumatic stress disorder Hormone receptor Cardiology Gestation Female Cardiology and Cardiovascular Medicine business Biomarkers Hormone |
Zdroj: | Clinical Research in Cardiology. 108:831-846 |
ISSN: | 1861-0692 1861-0684 |
DOI: | 10.1007/s00392-019-01441-x |
Popis: | Hormones have a vital duty in the conservation of physiological cardiovascular function during pregnancy. Alterations in oestrogen, progesterone and prolactin levels are associated with changes in the cardiovascular system to support the growing foetus and counteract pregnancy stresses. Pregnancy hormones are, however, also linked to numerous pathophysiological outcomes on the cardiovascular system. The expression and effects of the three main pregnancy hormones (oestrogen, prolactin and progesterone) vary depending on the gestation period. However, the reaction of a target cell also depends on the abundance of hormone receptors and impacts put forth by other hormones. Hormonal interaction may be synergistic, antagonistic or permissive. It is crucial to explore the cross talk of pregnancy hormones during gestation, as this may have a greater impact on the overall changes to the cardiovascular system. |
Databáze: | OpenAIRE |
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