Evaluating Autologous Lipofilling for Parry-Romberg Syndrome–Associated Defects: A Systematic Literature Review and Case Report
| Autor: | Vicky Kang, Yvonne E. Kaptein, Karina P. Quinn, James Roring, Anuja K. Antony, Ryan J. Jacobs, Katherine A. Rodby |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Free flap 030230 surgery Free Tissue Flaps 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Disease severity Facial Hemiatrophy medicine Humans Craniofacial business.industry Soft tissue Parry–Romberg syndrome Plastic Surgery Procedures medicine.disease Surgery Progressive Hemifacial Atrophy Systematic review Adipose Tissue Otorhinolaryngology Inclusion and exclusion criteria Oral Surgery business |
| Zdroj: | The Cleft Palate-Craniofacial Journal. 53:339-350 |
| ISSN: | 1545-1569 1055-6656 |
| DOI: | 10.1597/14-232 |
| Popis: | Background Parry-Romberg syndrome (PRS) is a rare craniofacial disease that causes progressive hemifacial atrophy of the soft tissue before spontaneously entering remission. Autologous fat grafting may provide a less invasive alternative, producing aesthetically pleasing results while avoiding the need for traditional microsurgical free flap coverage. Methods A systematic review of the literature was conducted. Inclusion and exclusion criteria were applied. The case report highlights the technique using two-dimensional and three-dimensional photography. Results Our review yielded 31 articles in addition to our case describing 147 cases of lipofilling to correct PRS soft-tissue defects. Patients underwent an average of 2.2 procedures, receiving on average 95 mL of grafted fat. Disease severity was classified into mild (41%), moderate (42%), and severe (17%) in the identified patients. Increasing disease severity correlated with an increasing number of procedures and fat-grafting volumes to achieve adequate aesthetic outcomes (mean, 1.5 and 38 mL; 2.3 and 81 mL; 3.7 and 129 mL, respectively). Reported benefits over flap-based reconstructions included reductions in cost (40%), operative time (50%), donor-site morbidity (52%), and rate of complications (33%). Aesthetic benefits cited included improved skin quality (65%), more natural contours (1%), and more natural facial expressions (10%). Conclusion Fat grafting for correction of PRS-associated soft-tissue defects is receiving heightened acceptance for its ability to restore natural facial contours. While additional fat-grafting procedures may be required with increased disease severity, autologous fat grafting may be a beneficial option as a sole modality to correct PRS-associated soft-tissue atrophy. |
| Databáze: | OpenAIRE |
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