Short communication: The effect of genotyping cows to improve the reliability of genomic predictions for selection candidates
| Autor: | Christian Edel, Kay-Uwe Götz, Reiner Emmerling, L. Plieschke, E.C.G. Pimentel |
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| Rok vydání: | 2016 |
| Předmět: |
Male
0301 basic medicine Genotype Fleckvieh cattle Breeding program media_common.quotation_subject biology.animal_breed Pedigree chart Breeding 03 medical and health sciences Germany Genetics Animals Selection Genetic Genotyping Selection (genetic algorithm) media_common Daughter Genome biology Sire 0402 animal and dairy science Reproducibility of Results Genomics 04 agricultural and veterinary sciences Heritability 040201 dairy & animal science Pedigree Phenotype 030104 developmental biology Haplotypes Austria Cattle Female Animal Science and Zoology Food Science |
| Zdroj: | Journal of Dairy Science. 99:1999-2004 |
| ISSN: | 0022-0302 |
| DOI: | 10.3168/jds.2015-10246 |
| Popis: | In this study we investigate the potential of enlarging the reference population for genomic prediction in dairy cattle by routinely genotyping a random sample of the first-crop daughters of every AI bull in the breeding program. We analyzed small nuclear pedigrees, each consisting of a genotyped selection candidate and 3 generations of genotyped male ancestors. Genotypes were taken from the genomic routine evaluation of Fleckvieh cattle in Germany and Austria. The phenotypic information of a daughter of any one male in each of these pedigrees was either considered to be part of the daughter yield deviation of the corresponding sire, or was assumed to be an individually observed genotyped daughter of this sire. Daughter genotypes in this case were simulated from phased haplotypes of their sires and random maternal gametes drawn from a haplotype library. We measured the gain from genotyping daughters as the increase in model-based theoretical reliability of the genomic prediction for a putative selection candidate. We expressed the improvements as a marginal increase, corresponding to an increase in reliability at a reliability baseline level of zero, to simplify comparisons. Results were encouraging with 2 to 40% of marginal reliability increase for selection candidates depending on the assumed heritability of the trait and the number of daughters modeled to be genotyped in the design. |
| Databáze: | OpenAIRE |
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