Current Status and Prospects of Targeted Therapy for Osteosarcoma

Autor:	Zunguo Hu, Shuang Wen, Zijun Huo, Qing Wang, Jiantao Zhao, Zihao Wang, Yanchun Chen, Lingyun Zhang, Fenghua Zhou, Zhangyu Guo, Huancai Liu, Shuanhu Zhou
Rok vydání:	2022
Předmět:	Osteosarcoma Humans Immunologic Factors Bone Neoplasms General Medicine Molecular Targeted Therapy Bone and Bones
Zdroj:	Cells. 11(21)
ISSN:	2073-4409
Popis:	Osteosarcoma (OS) is a highly malignant tumor occurring in bone tissue with a high propensity to metastasize, and its underlying mechanisms remain largely elusive. The OS prognosis is poor, and improving the survival of OS patients remains a challenge. Current treatment methods such as surgical approaches, chemotherapeutic drugs, and immunotherapeutic drugs remain ineffective. As research progresses, targeted therapy is gradually becoming irreplaceable. In this review, several treatment modalities for osteosarcoma, such as surgery, chemotherapy, and immunotherapy, are briefly described, followed by a discussion of targeted therapy, the important targets, and new technologies for osteosarcoma treatment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151ee2833253a0a0e8d29e3c1cabb010 https://pubmed.ncbi.nlm.nih.gov/36359903 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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