Optimal designs for phase II/III drug development programs facilitated by R Shiny applications

Autor:	Preussler, S, Kirchner, M, Götte, H, Kieser, M
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	ddc: 610 phase II/III drug development program R shiny application 610 Medical sciences Medicine bias adjustment optimization sample size multi-arm
Zdroj:	64. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS); 20190908-20190911; Dortmund; DOCAbstr. 168 /20190906/
DOI:	10.3205/19gmds006
Popis:	Introduction: Recently, a utility-based approach was proposed to optimize planning of phase II/III drug development programs in terms of sample size allocation and go/no-go decision rules (whether to stop or to proceed to phase III) [ref:1]. The utility function takes into account[for full text, please go to the a.m. URL] 64. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Databáze:	OpenAIRE
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