Diagnostic and Therapeutic Difficulties in Carotid Body Paragangliomas, Based on Clinical Experience and a Review of the Literature
| Autor: | Mariusz Chabowski, Andrzej T. Dorobisz, Tomasz Zatoński, Marzena Kubacka, Hanna Temporale, Tomasz Krecicki, Dariusz Janczak, Karolina Dorobisz, Tadeusz Dorobisz |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty External carotid artery Medicine (miscellaneous) 030204 cardiovascular system & hematology Anastomosis Carotid Body Tumor Carotid paraganglioma General Biochemistry Genetics and Molecular Biology Paraganglioma 03 medical and health sciences 0302 clinical medicine medicine.artery Internal Medicine medicine Humans Pharmacology (medical) Genetics (clinical) business.industry Middle Aged Carotid Body Paraganglioma medicine.disease Surgery medicine.anatomical_structure Otorhinolaryngology Reviews and References (medical) cardiovascular system Female Carotid body Radiology Internal carotid artery business 030217 neurology & neurosurgery |
| Zdroj: | Advances in Clinical and Experimental Medicine. 25:1173-1177 |
| ISSN: | 1899-5276 |
| Popis: | Background Paragangliomas are rare neuroendocrine tumors, representing 0.03% of all tumors. Half of them develop in the head and neck, and among these 50% are sporadic cervical tumors. Objectives The aim of the study was to carry out an epidemiological and clinical analysis of paraganglioma patients diagnosed and treated at the authors' clinics between 1985 and 2014. Material and methods The medical data of 47 patients were analyzed. All the patients were qualified for surgery. In 43 cases (88%), simple resection of the tumor was performed, including 11 cases (22%) that additionally required vascular suturing, and 5 (10%) that required reconstruction of the internal carotid artery. Carotid vessel repair was performed by shortening the internal carotid artery in 3 cases (6%), using a saphenous vein graft in 2 cases (4%), and by creating an anastomosis between the external carotid artery and the distal portion of the internal carotid artery in one case (2%). Results In 40 cases (82%), the course of treatment was uneventful. Three patients (6%) were reoperated because of symptoms of cerebral stroke. Palsy of the hypoglossal nerve occurred in 3 cases (6%), and facial nerve palsy in 2 patients (4%). Six patients (12%) developed postoperative hematomas in the wound. In all the cases, histopathological examinations confirmed carotid paraganglioma. Conclusions Cooperation with an otolaryngologist and vascular surgeon during surgery is recommended due to frequent damage to carotid vessels by carotid paragangliomas. Detection of the tumor in the early stages improves surgical treatment outcomes and reduces the number of complications. Regular postoperative check-ups are necessary due to possible occurrences of multiple tumors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|