Cortical Folding Patterns and Predicting Cytoarchitecture
| Autor: | Katrin Amunts, Oliver Hinds, Karl Zilles, B.T. Thomas Yeo, Jean C. Augustinack, Evelina Busa, Bruce Fischl, Niranjini Rajendran, Hartmut Mohlberg |
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| Přispěvatelé: | Harvard University--MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory, McGovern Institute for Brain Research at MIT, Fischl, Bruce, Hinds, Oliver, Yeo, B. T. Thomas |
| Rok vydání: | 2007 |
| Předmět: |
Cognitive Neuroscience
education Brain mapping 050105 experimental psychology 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Predictive Value of Tests medicine Humans 0501 psychology and cognitive sciences Cerebral Cortex Brain Mapping Basilar Artery Stenosis Extramural 05 social sciences Articles Folding (DSP implementation) macroscopic landmarks microscopic architecture 3. Good health medicine.anatomical_structure Cytoarchitecture Cerebral cortex Psychology Neuroscience morphometry 030217 neurology & neurosurgery Brodmann area |
| Zdroj: | Cerebral Cortex (New York, NY) Oxford |
| ISSN: | 1460-2199 1047-3211 |
| DOI: | 10.1093/cercor/bhm225 |
| Popis: | The human cerebral cortex is made up of a mosaic of structural areas, frequently referred to as Brodmann areas (BAs). Despite the widespread use of cortical folding patterns to perform ad hoc estimations of the locations of the BAs, little is understood regarding 1) how variable the position of a given BA is with respect to the folds, 2) whether the location of some BAs is more variable than others, and 3) whether the variability is related to the level of a BA in a putative cortical hierarchy. We use whole-brain histology of 10 postmortem human brains and surface-based analysis to test how well the folds predict the locations of the BAs. We show that higher order cortical areas exhibit more variability than primary and secondary areas and that the folds are much better predictors of the BAs than had been previously thought. These results further highlight the significance of cortical folding patterns and suggest a common mechanism for the development of the folds and the cytoarchitectonic fields. National Center for Research Resources (U.S.) (P41-RR14075) National Center for Research Resources (U.S.) (R01-RR16594-01A1) National Center for Research Resources (U.S.) (NCRR BIRN Morphometric Project BIRN002, U24 RR021382) National Institute of Biomedical Imaging and Bioengineering (U.S.) (R01 EB001550) National Institute of Biomedical Imaging and Bioengineering (U.S.) (R01 EB006758) National Institute of Neurological Disorders and Stroke (U.S.) (R01 NS052585-01) Mental Illness and Neuroscience Discovery (MIND) Institute National Institutes of Health (U.S.) (NIH Roadmap for Medical Research (grant U54 EB005149)) Hermann von Helmholtz-Gemeinschaft Deutscher Forschungszentren Deutsche Forschungsgemeinschaft (DFG) National Institutes of Health. National Institute for Biomedical Imaging and Bioengineering National Institute of Neurological Disorders and Stroke (U.S.) National Institute of Mental Health (U.S.) |
| Databáze: | OpenAIRE |
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