Cerebral Vascular Accident in Young Women: A Problem for Pregnancy and Contraception? Report of Two Cases
Autor: | Zimmermann Jb, Barbosa Inl, Pacheco Gan, Sant-Ana Gmc, Pinto Cdc, Fonseca Cc, Faria Lp, Barreto Ic, Fernandes Alm, Silva Lff, Mata Ds, Mourão Pa, Amaral Vm, Resende Laf, Gribel Lh, Araujo Ahsl, Caplum Mc, Luz Ms |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Disease Case Reports 030204 cardiovascular system & hematology Thrombophilia Preeclampsia 03 medical and health sciences 0302 clinical medicine Pregnancy Ischemic medicine Eclampsia Stroke Hemorrhagic business.industry Obstetrics Incidence (epidemiology) Asploro Journal of Biomedical and Clinical Case Reports General Medicine medicine.disease Cerebrovascular Disease Gestation business 030217 neurology & neurosurgery |
Popis: | Cerebrovascular disease (CVD) is a neurological medical emergency and one of the main causes of death worldwide; it is classified as ischemic or hemorrhagic. The disease is one of the most severe clinical events related to pregnancy due to thrombogenesis and thrombophilia; there is an incidence of 25 to 34 CVD per 100 thousand births. The current research reports two cases of stroke episode, one previous and another during pregnancy, as well as their associated complications. The first patient had hereditary thrombophilia caused by PAI 4G/5G polymorphism and previous stroke; however, she had regular pregnancy. The second patient had hereditary thrombophilia caused by protein C deficit, had a stroke during pregnancy, and preeclampsia in the first gestational semester; therefore, she was subjected to the cesarean section on the 35thweek of pregnancy. Stroke episodes during pregnancy can be very aggressive because it can lead to death or disabilities, not only in the mother but also in the fetus. Based on the association between thrombotic processes and complications, prophylactic anticoagulant therapy is recommended for women with thrombophilia who had a stroke and/or certain adverse pregnancy outcomes, such as recurrent miscarriages. |
Databáze: | OpenAIRE |
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