Ductal carcinoma in situ of the breast results of conservative and radical treatments in 716 patients
| Autor: | J.-C. Charpentier, V. Servent, S. Giard, R. Fay, H. Auvray, C. Charra-Brunaud, B. De Lafontan, C. Cohen-Solal-Le Nir, Bruno Cutuli, Frédérique Penault-Llorca, V. Fichet, Hervé Mignotte |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Cancer Research medicine.medical_specialty medicine.medical_treatment Mammary gland Breast Neoplasms Disease-Free Survival Metastasis Risk Factors medicine Humans Risk factor Neoplasm Metastasis Aged Retrospective Studies Gynecology Aged 80 and over business.industry Carcinoma in situ Carcinoma Ductal Breast Cancer Ductal carcinoma Middle Aged medicine.disease Radiation therapy medicine.anatomical_structure Oncology Multivariate Analysis Regression Analysis Female Neoplasm Recurrence Local Nuclear medicine business Mastectomy Carcinoma in Situ |
| Zdroj: | European journal of cancer (Oxford, England : 1990). 37(18) |
| ISSN: | 0959-8049 |
| Popis: | Until now, less than 5% of the patients with breast ductal carcinoma in situ (DCIS) have been enrolled in clinical trials. Consequently, we have analysed the results of ‘current practice’ among 716 women treated in eight French Cancer Centres from 1985 to 1992: 441 cases (61.6%) corresponded to impalpable lesions, 92 had a clinical size of less than or equal to 2 cm and 70 from 2 to 5 cm; in 113 cases, the size was unspecified. Median age was 53.2 years (range: 21–87 years). 145 patients underwent mastectomy (RS) and 571 conservative surgery (CS) without (136) or with (435) radiotherapy (CS+RT). The mean histological tumour sizes in these three groups were 25.6, 8.2, 14.8 mm, respectively (P |
| Databáze: | OpenAIRE |
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