| Autor: |
Josephine, Harrington, W Schuyler, Jones, Jacob A, Udell, Karen, Hannan, Deepak L, Bhatt, Stefan D, Anker, Mark C, Petrie, Ola, Vedin, Javed, Butler, Adrian F, Hernandez |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
JACC: Heart Failure. 10:404-414 |
| ISSN: |
2213-1779 |
| DOI: |
10.1016/j.jchf.2022.02.008 |
| Popis: |
Acute coronary syndrome (ACS) is frequently complicated by evidence of heart failure (HF). Those at highest risk for acute decompensated HF in the setting of ACS (ACS-HF) are older, female, and have preexisting heart disease, type 2 diabetes mellitus, hypertension, and/or kidney disease. The presence of ACS-HF is strongly associated with higher mortality and more frequent readmissions, especially for HF. Low implementation of guideline-directed medical therapy has further complicated the clinical care of this high-risk population. Improved utilization of current therapies, coupled with further investigation of strategies to manage ACS-HF, is desperately needed to improve outcomes in this vulnerable population, and the results of currently ongoing or recently concluded ACS-HF studies in this population are of great interest. In this review, we explore the pathophysiology, epidemiology, risk factors, and outcomes for patients with ACS-HF, and describe both existing evidence for management of this challenging condition and areas requiring further research. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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