Autor: |
Jinrong He, Xu Yang, Liangqun Hua, Yongjun Chen, Weiwei Huang, Chao Ye, Hongmei Bai, Mingcui Yuan, Zhongqian Yang, Fulan Gao, Sijin Li, Yanbing Ma, Qishu Zhang, Wenjia Sun, Weiran Li |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
ACS Applied Materials & Interfaces. 12:54399-54414 |
ISSN: |
1944-8252 1944-8244 |
Popis: |
Tumor vaccines based on synthetic human papillomavirus (HPV) oncoprotein E7 and/or E6 peptides have shown encouraging results in preclinical model studies and human clinical trials. However, the clinical efficacy may be limited by the disadvantages of vulnerability to enzymatic degradation and low immunogenicity of peptides. To further improve the potency of vaccine, we developed a poly(lactide |
Databáze: |
OpenAIRE |
Externí odkaz: |
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