Tylosis A with squamous cell carcinoma of the oesophagus in a Spanish family
| Autor: | Pamela Estévez Boullosa, Antonio Brage Varela, Jesús García Silva, Marta María Blanco Rodríguez |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Keratoderma Palmoplantar Diffuse Pathology medicine.medical_specialty Esophageal Neoplasms Hyperkeratosis Young Adult medicine Humans Basal cell carcinoma Esophagus Keratoderma Aged Hepatology business.industry Incidence (epidemiology) Gastroenterology Middle Aged medicine.disease Dyskeratosis medicine.anatomical_structure Epidermoid carcinoma Tylosis Genetic Loci Spain Child Preschool Carcinoma Squamous Cell Female business Chromosomes Human Pair 17 |
| Zdroj: | European journal of gastroenterologyhepatology. 23(3) |
| ISSN: | 1473-5687 |
| Popis: | Palmoplantar tylosis is a focal nonepidermolytic palmoplantar hyperkeratosis, which is inherited as an autosomal dominant condition. Two types have been described: an early onset type B tylosis, which occurs in the first year of life and is usually benign, and type A tylosis, which occurs between the ages of 5 and 15 years. Type A tylosis has been associated with a high incidence of oesophageal carcinoma in three families in England, Germany and the USA. This study describes an additional family from Spain with tylosis A, without any known relation to those described before. |
| Databáze: | OpenAIRE |
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