A multicenter, prospective evaluation of the Chinese Society of Thrombosis and Hemostasis Scoring System for disseminated intravascular coagulation
| Autor: | Ming Hou, Ying Feng, Heng Mei, Tienan Zhu, Zeping Zhou, Ting Niu, Yu Hu, Lei Su, Feng Xue, Lin-Hua Yang, Ruibin Huang, Yan Li, Lili Luo, Jun Peng, Yuhong Zhou, Qiulan Ding, Ying-Ying Wu, Jianming Feng, Jian Gu, Xiao-Hui Zhang, Jun Deng, Yue Han, Xiaomin Wang |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male China medicine.medical_specialty Concordance 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases Internal medicine Odds Ratio Humans Medicine Prospective Studies Prospective cohort study Societies Medical APACHE Disseminated intravascular coagulation Hemostasis Receiver operating characteristic APACHE II business.industry Gold standard Hematology Disseminated Intravascular Coagulation Middle Aged Prognosis medicine.disease ROC Curve 030220 oncology & carcinogenesis Female SOFA score business circulatory and respiratory physiology |
| Zdroj: | Thrombosis Research. 173:131-140 |
| ISSN: | 0049-3848 |
| Popis: | Disseminated intravascular coagulation (DIC) is a severe complication of critical conditions. There are several scoring systems used for the diagnosis of DIC, including the International Society on Thrombosis and Hemostasis (ISTH) Overt-DIC criteria, the Japanese Ministry of Health and Welfare (JMHW) criteria and the Chinese Society of Thrombosis and Hemostasis scoring system for DIC (CDSS). The objective of this prospective study was to evaluate the accuracy and predictive value of the CDSS.1318 patients, aged 18-70 years old and suspected of DIC were enrolled from 18 hospitals across China. Participants were divided into two groups for analysis (group 1, non-hematological diseases; group 2, hematological diseases). 242 patients were excluded because of incomplete data collection and failure to follow-up.The rates of concordance of diagnosis of DIC between the CDSS and two other scoring systems were close to 80%. The area under ROC curves of CDSS had a slight advantage when using the ISTH, JMHW criteria or prognosis as gold standard, respectively. The CDSS DIC was an independent predictor of mortality, and its odds-ratio was superior or comparable to that of the ISTH and JMHW criteria in the two groups. The CDSS DIC score also had a significant correlation with the APACHE II and SOFA score (p 0.05). In summary, as a quantification standard of the Chinese experts' consensus, the CDSS is conducive to the standardized diagnosis of DIC because of its favorable diagnostic and prognostic utility. |
| Databáze: | OpenAIRE |
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