Risk factors for catheter-related bloodstream infections in adult hospitalized patients - multicenter cohort study

Autor:	Chikaaki Nakamichi, Ryozo Kobayashi, Tadateru Takahashi, Mataro Goto, Nobutomo Miyanari, Hiroya Mizusawa, Shoichiro Koike, Yoshio Haga
Rok vydání:	2013
Předmět:	Microbiology (medical) Adult Male medicine.medical_specialty Pediatrics Catheterization Cohort Studies Japan Risk Factors Internal medicine Sepsis medicine Infection control Central Venous Catheters Humans Prospective Studies Risk factor Internal jugular vein Aged Aged 80 and over Univariate analysis General Immunology and Microbiology business.industry Incidence (epidemiology) Incidence General Medicine Middle Aged Hospitals Exact test Catheter Infectious Diseases Catheter-Related Infections Female business Cohort study
Zdroj:	Scandinavian journal of infectious diseases. 45(10)
ISSN:	1651-1980
Popis:	Risk factors for catheter-related bloodstream infections (CRBSIs) may change over time with progress in infection control. This study was undertaken to explore the current risk factors for CRBSIs in hospitalized patients.Adult patients with non-tunneled central venous catheters (CVCs) in 12 Japanese referral hospitals were prospectively enrolled between December 2009 and January 2012. Patients were monitored for CRBSIs for up to 8 weeks from CVC insertion; data were collected regarding patient characteristics, the purpose of CVC insertion, insertion methods, mechanical complications during insertion, and post-insertion catheter care.A total of 892 patients were enrolled in this study. The overall incidence of CRBSIs was 0.40 infections per 1000 catheter-days. Univariate analysis using the Fisher's exact test identified one of the participating hospitals (hospital A; p0.001), internal jugular vein catheterization (IJVC) (p = 0.0013), not using maximal sterile barrier precautions (p = 0.030), and the Seldinger technique for catheter insertion (p = 0.025) as significant risk factors for CRBSI. After excluding data from hospital A, only IJVC remained a significant risk factor for CRBSI (p = 0.025). The cumulative probability of remaining without CRBSI was significantly lower in patients with IJVCs than in patients with other catheter routes (p0.001; log-rank test). Similarly, the cumulative probability of remaining without catheter removal due to a suspected infection was significantly lower in patients with IJVCs (p = 0.034; log-rank test).The current study suggests that IJVC might be a risk factor for CRBSI under current infection control conditions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e274f56bf396afc09acdbbcb70a0d7 https://pubmed.ncbi.nlm.nih.gov/23848411 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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