A Report of Nausea and Vomiting with Discontinuation of Chronic Use ofSalvia divinorum
| Autor: | Karen F. Marlowe, G. A. Ray, C. R. Travis |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Abdominal discomfort
medicine.medical_specialty Traditional medicine biology Nausea business.industry lcsh:R lcsh:Medicine Case Report General Medicine biology.organism_classification Salvinorin A Discontinuation chemistry.chemical_compound Diarrhea Opioid chemistry Internal medicine Salvia divinorum medicine Vomiting medicine.symptom business medicine.drug |
| Zdroj: | Case Reports in Medicine, Vol 2012 (2012) Case Reports in Medicine |
| ISSN: | 1687-9635 1687-9627 |
| DOI: | 10.1155/2012/543747 |
| Popis: | Introduction. This is the first reported case of gastrointestinal symptoms associated with withdrawal after chronic use of this substance.Case Presentation. A 51-year-old Caucasian woman was referred to a hospital with a 3-day history of nausea, vomiting, diarrhea, and abdominal discomfort. She reported no sick family members or contact with anyone who was ill. She did report smoking 3–5 cigarettes of the herb “Salvia” consistently for 3-4 months and quit approximately 48 hours before symptoms appeared. Her use of the herb had been consistent; she smoked several cigarettes each day. Laboratory results were essentially normal including the white blood cell count. She received symptomatic treatment and was released after one day.Discussion. Salvinorin A, a kappa-opioid receptor agonist, is the major active ingredient ofS. divinorum. The unique opioid properties of this herb may explain its ability to cause changes in intestinal transit time.Conclusion. A 51-year-old woman possibly developed gastrointestinal manifestations suggestive of withdrawal fromSalvia divinorumafter smoking the substance consistently for 3 to 4 months. The widespread use of this herb will make the potential for withdrawal syndromes more commonplace. |
| Databáze: | OpenAIRE |
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