Amorolfine vs. ciclopirox – lacquers for the treatment of onychomycosis
| Autor: | Wojciech Bienias, Katarzyna Tabara, Andrzej Kaszuba, Agnieszka Wojciechowska, Marta Pastuszka, Magdalena Oszukowska, Anna Szewczyk |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Antifungal
Review Paper Ciclopirox Itraconazole medicine.drug_class business.industry ciclopirox amorolfine Dermatology Nail plate Pharmacology medicine.anatomical_structure Drug delivery Amorolfine onychomycosis lacquer medicine Nail (anatomy) Immunology and Allergy Terbinafine business medicine.drug |
| Zdroj: | Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii |
| ISSN: | 1642-395X |
| DOI: | 10.5114/pdia.2014.40968 |
| Popis: | Amorolfine 5% and ciclopirox 8% nail lacquers are commonly used in topical treatment of onychomycosis. These formulations may be used alone or in combination with oral antifungal agents. Amorolfine and ciclopirox are valuable therapeutic options, however, their usage in monotherapy should be limited. Proper amorolfine and ciclopirox penetration through the nail plate is provided by transungual drug delivery systems. Although amorolfine and ciclopirox have a different mode of action, they both exhibit a broad antifungal activity. The use of antifungal nail lacquers in combination with oral agents, such as terbinafine and itraconazole, improves efficacy of antifungal therapy. |
| Databáze: | OpenAIRE |
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