Proliferation characteristics of erythroblasts in chronic renal failure
| Autor: | U. Kempgens, B. Schautt, M. Mayer, W. Queisser |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Erythrocytes Erythroblasts Cell Bone Marrow Cells Biology Photometry Polyploidy Andrology chemistry.chemical_compound Bone Marrow Internal medicine medicine Humans Aged Hematology DNA synthesis General Medicine Middle Aged Diploidy In vitro medicine.anatomical_structure chemistry Autoradiography Kidney Failure Chronic Chronic renal failure Female Bone marrow Ploidy Cell Division DNA |
| Zdroj: | Blut. 35:45-50 |
| ISSN: | 1432-0584 0006-5242 |
| DOI: | 10.1007/bf01006963 |
| Popis: | Proliferation of bone marrow erythroblasts in patients with chronic renal disease was studied by combined application of cytophotometric measurement of the DNA content and 3H-TdR labeling in vitro. A striking decrease of 3H-TdR labeling was found in most of the cases. The proportion of diploid (G0 + G1) as well as of tetraploid unlabeled cells (G2) was increased. The data suggest a disturbed induction of DNA synthesis of resting cells as well as an arrest of cells in G2 being responsable for ineffective cell production in this disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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