Endogenous fatty acid synthesis in squamous cell carcinomas of the oral cavity
| Autor: | Chuan-Bin Guo, Qing Song, Ding-xin Liu, Shu-cong Meng, Guang-Yan Yu, Lian-hui Cui |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Pathology
medicine.medical_specialty Cell Adipose tissue Endogeny Acetic acid chemistry.chemical_compound Carcinoma Medicine Humans Carbon Radioisotopes Fatty acid synthesis business.industry Fatty Acids Mouth Mucosa medicine.disease Molecular biology medicine.anatomical_structure Otorhinolaryngology Epidermoid carcinoma chemistry Carcinoma Squamous Cell Scintillation Counting Surgery Mouth Neoplasms Oral Surgery business Ex vivo |
| Zdroj: | The British journal of oralmaxillofacial surgery. 38(5) |
| ISSN: | 0266-4356 |
| Popis: | We measured the synthesis of endogenous fatty acids in oral squamous cell carcinoma, its adjacent tissue, and normal oral tissues that were collected fresh from surgical specimens. The tissues were minced in Roswell Park Memorial Institute Medium 1640 (RPMI 1640) and incubated in [1(2)-(14)C] acetic acid, sodium salt ((14)CH(3)(14)CO(2)Na). Total lipids were then extracted and(14)C was measured by scintillation counter. We found that incorporation of(14)C in the total lipids of squamous cell carcinoma was significantly higher than in the other tissues. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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