Dictyotadimer A, a new dissymmetric bis-diterpene from a brown alga of the genus Dictyota
| Autor: | Mohamed El Hattab, Dominique Bonhomme, Yves Blache, Olivier P. Thomas, Yannick Viano, Annick Ortalo-Magné, Gérald Culioli, Louis Piovetti |
|---|---|
| Přispěvatelé: | Laboratoire Matériaux Polymères Interfaces Environnement Marin - EA 4323 (MAPIEM), Université de Toulon (UTLN), Metabolomique Marine Environnementale, Institut de Chimie de Nice (ICN), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA) |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Molecular model
biology 010405 organic chemistry Chemistry Stereochemistry Chemical structure Dimer Organic Chemistry 010402 general chemistry Mass spectrometry biology.organism_classification 01 natural sciences Biochemistry Terpenoid 0104 chemical sciences chemistry.chemical_compound Drug Discovery Dictyotaceae Diterpene [SDE.BE]Environmental Sciences/Biodiversity and Ecology Two-dimensional nuclear magnetic resonance spectroscopy ComputingMilieux_MISCELLANEOUS |
| Zdroj: | Tetrahedron Letters Tetrahedron Letters, 2011, 52 (9), pp.1031--1035. ⟨10.1016/j.tetlet.2010.12.095⟩ |
| DOI: | 10.1016/j.tetlet.2010.12.095⟩ |
| Popis: | A phytochemical investigation of a Mediterranean brown alga (Dictyota sp.) led to the isolation of a novel C40 bis-diterpene, named dictyotadimer A. The chemical structure of this unusual dissymmetric dimer, characterized by a C–C linkage between two different xenicane units, was elucidated by 1D and 2D NMR analyses together with HR-ESI mass spectrometry. The relative configuration of the two diterpenoid components was determined by NOESY NMR correlations and molecular modeling. A plausible biogenetic pathway of dictyotadimer A was also proposed. |
| Databáze: | OpenAIRE |
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