Functional analysis reveals that Tinagl1 is required for normal muscle development in mice through the activation of ERK signaling

Autor:	Yoriko Sato, Keisuke Kawashima, Emiko Fukui, Hiromichi Matsumoto, Fumiaki Yoshizawa, Yusuke Sato
Rok vydání:	2022
Předmět:	Mice Knockout MAP Kinase Signaling System Endothelial Cells Cell Biology Muscle Development Lipocalins Neoplasm Proteins Myoblasts Mice Animals Female Muscle Skeletal Molecular Biology Transcription Factors
Zdroj:	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1869:119294
ISSN:	0167-4889
DOI:	10.1016/j.bbamcr.2022.119294
Popis:	Tinagl1 (tubulointerstitial nephritis antigen-like 1) is a matricellular protein involved in female infertility and breast cancer tumorigenesis. In this study, we analyzed the function of Tinagl1 in skeletal muscle using knockout mice and cell experiments. Although primary myoblasts isolated from Tinagl1-decifient (Tinagl1
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b7e0f11c1540db788744cdfabf8e43 https://doi.org/10.1016/j.bbamcr.2022.119294 Zobrazit plný text záznamu Full Text from ScienceDirect