A comparative clinical and mycological study of Nd-YAG laser versus topical terbinafine in the treatment of onychomycosis
| Autor: | Raghda Ahmed Zaki Talaat, Esraa E El-Hawary, Rania A. El-Tatawy, Naeim M Abd El-Naby |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Long pulse Antifungal Agents Light Administration Oral Topical treatment Dermatology Lasers Solid-State Naphthalenes Administration Cutaneous Group B Young Adult Laser therapy Trichophyton Onychomycosis medicine Effective treatment Humans Terbinafine business.industry Middle Aged Treatment Outcome Nd:YAG laser Drug Therapy Combination Female business medicine.drug |
| Zdroj: | The Journal of dermatological treatment. 26(5) |
| ISSN: | 1471-1753 |
| Popis: | Topical treatment of onychomycoses is time consuming, cost-intensive and subject to relatively high failure rates. Light-based devices may be effective treatment modalities. Aim of this work: To compare the clinical and mycological efficacy of Nd-YAG laser versus topical terbinafine in the treatment of onychomycosis.This study included 40 patients with onychomycosis randomized to receive four sessions of Nd-YAG laser (group A) or topical terbinafine twice daily for six months (group B). Follow-up was performed monthly. Mycological examination was done at third and sixth months following the start of treatment.After six months, all patients in group A showed marked improvement, while in group B only 50% of patients showed mild to moderate improvement. In addition, by the end of six months, 80% of the patients in group A showed mycological clearance, while all patients in group B still had positive cultures.Long pulse Nd-YAG laser therapy of onychomycosis is a safe and efficient method for treating onychomycosis. It is especially beneficial in elderly, compromised and hepatopathic patients for whom other alternative treatments could present some risks. |
| Databáze: | OpenAIRE |
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