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OBJECTIVES: To assess dietary habits and psychological well-being during the COVID-19 lockdown in Italy, one of the European countries most severely affected by the first wave of the COVID-19 pandemic. METHODS: The #PRESTOinsieme project is a web-based survey open to people over 16 years of age that started on the 20(th) of March 2020 in Italy. Survey respondents underwent a set of validated questionnaires to assess dietary habits and psychological well-being (depression and posttraumatic stress, using the Center for Epidemiologic Studies Depression Scale and the Impact of Event Scale-Revised, respectively) during the lockdown. RESULTS: Survey respondents were 5008, with a median age of 38 years. The female gender was the most prevalent (63%). Dietary habits were found to be associated with psychological well-being. People suffering from moderate/severe depression symptoms and posttraumatic stress were found to have more frequently foods high in fat and sugars compared to people with no/mild depressive and posttraumatic stress symptoms (P-value 0.008). Furthermore, subjects with most severe depressive symptoms ate less frequently fruits (P-value |