A MRG-operated chromatin switch at SOC1 attenuates abiotic stress responses during the floral transition
Autor: | Julio Salinas, Manuel Piñeiro, Raquel Piqueras, Jose A. Jarillo, Javier Barrero-Gil, Alfonso Mouriz |
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Přispěvatelé: | Ministerio de Economía, Industria y Competitividad (España), Ministerio de Ciencia e Innovación (España), Ministerio de Educación (España), Agencia Estatal de Investigación (España), Barrero-Gil, J., Salinas, Julio, Piñeiro, Manuel, Barrero-Gil, J [0000-0003-0878-7576], Piqueras, R [0000-0003-4336-2709], Salinas, J [0000-0002-7694-0838], Jarillo, JA [0000-0002-2963-7641], Pineiro, M [0000-0002-4640-6511], Barrero-Gil, J. [0000-0003-0878-7576], Salinas, Julio [0000-0003-2020-0950], Piñeiro, Manuel [0000-0002-4640-6511] |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
0106 biological sciences
0301 basic medicine Upstream Research Report Physiology Chromosomal Proteins Non-Histone Cold-acclimation Arabidopsis Expression MADS Domain Proteins Plant Science Flowers 01 natural sciences Methylation Histone H4 03 medical and health sciences Histone H3 Stress Physiological Genetics Arabidopsis thaliana NuA4 histone acetyltransferase complex biology Abiotic stress Arabidopsis Proteins fungi food and beverages biology.organism_classification Cell biology Chromatin 030104 developmental biology Genes Genome-Wide Identification Function (biology) 010606 plant biology & botany |
Zdroj: | Plant Physiol Digital.CSIC. Repositorio Institucional del CSIC instname |
Popis: | 43 p.-5 fig. Plants react to environmental challenges by integrating external cues with endogenous signals to optimize survival and reproductive success. However, the mechanisms underlying this integration remain obscure. While stress conditions are known to impact plant development, how developmental transitions influence responses to adverse conditions has not been addressed. Here, we reveal a molecular mechanism of stress response attenuation during the onset of flowering in Arabidopsis (Arabidopsis thaliana). We show that Arabidopsis MORF-RELATED GENE (MRG) proteins, components of the NuA4 histone acetyltransferase complex that bind trimethylated-lysine 36 in histone H3 (H3K36me3), function as a chromatin switch on the floral integrator SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) to coordinate flowering initiation with plant responsiveness to hostile environments. MRG proteins are required to activate SOC1 expression during flowering induction by promoting histone H4 acetylation. In turn, SOC1 represses a broad array of genes that mediate abiotic stress responses. We propose that during the transition from vegetative to reproductive growth, the MRG-SOC1 module constitutes a central hub in a mechanism that tunes down stress responses to enhance the reproductive success and plant fitness at the expense of costly efforts for adaptation to challenging environments. This work was funded by the Ministerio de Economía,Industria y Competitividad, Gobierno de España (MINECO) ~grants BIO2016-77559-R (to J.A.J. and M.P.) and BIO2016-79187-R (to J.S.); the Ministerio de Ciencia e Innovación,Gobierno de España grant PID2019-104899GB-I00 (to J.A.J.and M.P.); a FPU fellowship from the Spanish Ministry of Education (to A.M.); The authors thank the “Severo Ochoa Program for Centres of Excellence in R&D” from the Agencia Estatal de Investigación of Spain (grant SEV-2016-0672(2017-2021) for supporting the scientific services used in this work. |
Databáze: | OpenAIRE |
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