Changes over a decade in psychotropic prescribing for people with intellectual disabilities: prospective cohort study
| Autor: | Angela Henderson, Linda Allan, Sally-Ann Cooper, Alasdair McIntosh, Deborah Kinnear, Colin McCowan, Paula McSkimming |
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| Přispěvatelé: | Medical Research Council, University of St Andrews. School of Medicine, University of St Andrews. Sir James Mackenzie Institute for Early Diagnosis, University of St Andrews. Population and Behavioural Science Division |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_treatment
Adult psychiatry 3rd-NDAS Cohort Studies Longitudinal Studies Prospective Studies Prospective cohort study Psychiatry Medicine(all) education.field_of_study General Medicine psychiatry Mental Health depression & mood disorders Medicine Mental health Clinical pharmacology Record linkage Schizophrenia & psychotic disorders Antipsychotic Agents Adult Psychosis medicine.medical_specialty BF Psychology Population schizophrenia & psychotic disorders BF R Medicine SDG 3 - Good Health and Well-being Intellectual Disability medicine Humans Bipolar disorder Medical prescription education Antipsychotic Psychotropic Drugs business.industry medicine.disease Cross-Sectional Studies Depression & mood disorders clinical pharmacology adult psychiatry business |
| Zdroj: | BMJ Open, Vol 10, Iss 9 (2020) BMJ Open BASE-Bielefeld Academic Search Engine |
| ISSN: | 2044-6055 |
| Popis: | ObjectivesTo investigate psychotropic prescribing in the intellectual disabilities population over 10 years, and associated mental ill health diagnoses.DesignComparison of cross-sectional data in 2002–2004 (T1) and 2014 (T2). Longitudinal cohort study with detailed health assessments at T1 and record linkage to T2 prescribing data.SettingGeneral community.Participants1190 adults with intellectual disabilities in T1 compared with 3906 adults with intellectual disabilities in T2. 545/1190 adults with intellectual disabilities in T1 were alive and their records linked to T2 prescribing data.Main outcome measuresEncashed regular and as-required psychotropic prescriptions.Results50.7% (603/1190) of adults in T1 and 48.2% (1881/3906) in T2 were prescribed at least one psychotropic; antipsychotics: 24.5% (292/1190) in T1 and 16.7% (653/3906) in T2; antidepressants: 11.2% (133/1190) in T1 and 19.1% (746/3906) in T2. 21.2% (62/292) prescribed antipsychotics in T1 had psychosis or bipolar disorder, 33.2% (97/292) had no mental ill health or problem behaviours, 20.6% (60/292) had problem behaviours but no psychosis or bipolar disorder. Psychotropics increased from 47.0% (256/545) in T1 to 57.8% (315/545) in T2 (pConclusionsDespite concerns about antipsychotic prescribing and guidelines recommending their withdrawal, it appears that while fewer antipsychotic prescriptions were initiated by T2 than in T1, people were not withdrawn from them once commenced. People with problem behaviours had increased prescribing. There was also a striking increase in antidepressant prescriptions. Adults with intellectual disabilities need frequent and careful medication reviews. |
| Databáze: | OpenAIRE |
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