The Bos taurus maternal microbiome: Role in determining the progeny early-life upper respiratory tract microbiome and health
| Autor: | M.L.S. Bicalho, Svetlana Lima, Rodrigo C. Bicalho |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Pulmonology Respiratory System Physiology Otology Ear Infections medicine.disease_cause Feces fluids and secretions Pregnancy Medicine and Health Sciences Prospective Studies Multidisciplinary biology Streptococcus Microbiota Genomics 04 agricultural and veterinary sciences Veterinary Diseases Medical Microbiology Vagina Medicine Female Anatomy Research Article DNA Bacterial Science Ear infection Microbial Genomics Microbiology 03 medical and health sciences Genetics medicine Animals Microbiome Bacteria Ruminococcus Organisms Middle Ear 0402 animal and dairy science Biology and Life Sciences Neonates Bacteroidetes Pneumonia medicine.disease biology.organism_classification 040201 dairy & animal science Otitis Media 030104 developmental biology Animals Newborn Otorhinolaryngology Ears Cattle Veterinary Science Bacteroides Head Biomarkers Developmental Biology |
| Zdroj: | PLoS ONE, Vol 14, Iss 3, p e0208014 (2019) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Natural transference of maternal microbes to the neonate, especially at birth via the vaginal canal, has recently been recognized in humans and cows; however, its microbial influence on calf health has not yet been documented. We compared the bacterial communities in vaginal and fecal samples from 81 pregnant dairy cows versus those in nasopharyngeal and fecal samples collected at 3, 14 and 35 days of life from their respective progeny. The microbiota of the calf upper respiratory tract (URT), regardless of calf age, was found to be highly similar to the maternal vaginal microbiota. Calf fecal microbiota clustered closely to the maternal fecal microbiota, progressing toward an adult-like state over the first 35 days when relative abundances of taxa were considered. Sixty-four, 65 and 87% of the detected OTUs were shared between cow and calf fecal microbiota at days 3, 14 and 35 respectively, whereas 73, 76 and 87% were shared between maternal vaginal microbiome and calf URT microbiota at days 3, 14 and 35, respectively. Bacteroidetes, Ruminococcus, Clostridium, and Blautia were the top four genera identified in maternal and calf fecal samples. Mannheimia, Moraxella, Bacteroides, Streptococcus and Pseudomonas were the top five genera identified in maternal vaginal and calf URT samples. Mannheimia was relatively more abundant in the vaginal microbiota of cows whose progeny were diagnosed with respiratory and middle ear disease. Our results indicate that maternal vaginal microbiota potentially influences the initial bacterial colonization of the calf URT, and that might have an important impact on the health of the calf respiratory tract and middle ear. |
| Databáze: | OpenAIRE |
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