Comparative Anti-Dandruff Efficacy between a Tar and a Non-Tar Shampoo
Autor: | Claudine Piérard-Franchimont, Valérie Vroome, Gloria C. Lin, Gérald Pierard, Yohini Appa |
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Rok vydání: | 2000 |
Předmět: |
Adult
Male medicine.medical_specialty viruses Hair Preparations Dermatology complex mixtures Clinical study chemistry.chemical_compound Keratolytic Agents Double-Blind Method otorhinolaryngologic diseases medicine Humans Coal tar Coal Tar Malassezia Piroctone olamine Traditional medicine business.industry Tar Dandruff Shampoo Scalp Dermatoses chemistry Malassezia furfur medicine.symptom business Salicylic acid medicine.drug |
Zdroj: | Dermatology. 200:181-184 |
ISSN: | 1421-9832 1018-8665 |
Popis: | A randomized double-blind clinical study was conducted on two groups of 30 volunteers using either a non-tar shampoo (2% salicylic acid, 0.75% piroctone olamine and 0.5% elubiol) or a 0.5% coal tar shampoo. Subjects were diagnosed as having moderate to marked dandruff. The study consisted of a 3-week washout, followed by a 4-week treatment and a 4-week posttreatment regression phase. The clinical evaluations and subject self-assessments showed that the non-tar shampoo was as effective as the tar shampoo. Both received high approval ratings (or =70%). Biometrological methods proved to be more sensitive than clinical evaluations to assess the efficacy of the shampoos. The non-tar shampoo yielded a significantly better reduction of Malassezia spp. counts (p0.02) during the treatment phase and reduced the spontaneous increase in squamometry values (p0.01) during the posttreatment phase. It is concluded that a formulation associating salicylic acid, piroctone olamine and elubiol exhibited increased beneficial effects compared to the coal tar shampoo. |
Databáze: | OpenAIRE |
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