Peripheral arthritis in patients with long-term inflammatory bowel disease. Results from 20 years of follow-up in the IBSEN study
| Autor: | Inger Camilla Solberg, Marte Lie Høivik, Øyvind Palm, Alvilde Maria Ossum, Milada Cvancarova, Morten H. Vatn, Bjørn Moum |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Peripheral arthritis Inflammatory bowel disease Severity of Illness Index Disease course 03 medical and health sciences Peripheral spondyloarthritis 0302 clinical medicine Medisinske Fag: 700 [VDP] Internal medicine Surveys and Questionnaires Spondylarthritis medicine Prevalence Humans In patient Artikkel VDP::Medisinske Fag: 700 Prospective Studies Aged 030203 arthritis & rheumatology Aged 80 and over Crohn's disease business.industry Norway Arthritis Gastroenterology Middle Aged medicine.disease Inflammatory Bowel Diseases INCEPTION COHORT Ulcerative colitis digestive system diseases Disease Progression 030211 gastroenterology & hepatology Female business Follow-Up Studies |
| Zdroj: | Scandinavian journal of gastroenterology. 53(10-11) |
| ISSN: | 1502-7708 |
| Popis: | Objectives: Peripheral arthritis and related musculoskeletal manifestations, often classified as peripheral spondyloarthritis, are frequently seen in patients with inflammatory bowel disease (IBD). Few long-term studies have reported on the prevalence of these conditions. The aim of this study was to determine the prevalence of IBD-related peripheral arthritis and peripheral spondyloarthritis in IBD patients during 20 years of disease course, and to assess whether these conditions were associated with the intestinal IBD severity and activity. Materials and methods: In an inception cohort (the IBSEN study), IBD patients were followed prospectively for 20 years. At the 5 year follow-up the patients underwent a rheumatological examination and at the 20 year follow-up they completed a questionnaire with identical questions. When peripheral arthritis was characteristic and not explained by other specific diagnoses, it was defined as IBD-related peripheral arthritis. The Assessment of Spondyloarthritis International Society criteria were used to define peripheral spondyloarthritis, including patients with peripheral arthritis, enthesitis and/or dactylitis. Results: After 20 years of follow-up, 441 patients were included (296 ulcerative colitis and 145 Crohn’s disease). The prevalence of IBD-related peripheral arthritis was 17.2% and peripheral spondyloarthritis 27.9% during the disease course. IBD severity and activity were not different between those with a history of IBD-related peripheral arthritis or peripheral spondyloarthritis and those without. A higher proportion of women had IBD-related peripheral arthritis and peripheral spondyloarthritis. Conclusion: During 20 years of disease course, more than every sixth patient had suffered from IBD-related peripheral arthritis and every fourth from peripheral spondyloarthritis. |
| Databáze: | OpenAIRE |
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