High prevalence of drug-resistant tuberculosis and other mycobacteria among HIV-infected patients in Brazil: a systematic review
| Autor: | Lucilaine Ferrazoli, Giselle B Klautau, Nilton José Fernandes Cavalcante, Ricardo Helbert Bammann, Valdir S Pinto, Marcelo Nóbrega Litvoc, Carla Maria Pasquareli Vazquez, Fernando A Fiúza de Melo, Liliana Aparecida Zamarioli |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Microbiology (medical)
Drug medicine.medical_specialty Tuberculosis lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 media_common.quotation_subject Antitubercular Agents lcsh:QR1-502 Mycobacterium Infections Nontuberculous Drug resistance lcsh:Microbiology Pharmacotherapy Internal medicine Tuberculosis Multidrug-Resistant Epidemiology Prevalence medicine Humans mycobacterial media_common High prevalence AIDS-Related Opportunistic Infections business.industry drug acquired immunodeficiency syndrome medicine.disease Regimen Systematic review tuberculosis resistant atypical Immunology Drug Therapy Combination business Brazil |
| Zdroj: | Memórias do Instituto Oswaldo Cruz., Vol 105, Iss 6, Pp 838-841 (2010) Memórias do Instituto Oswaldo Cruz, Volume: 105, Issue: 6, Pages: 838-841, Published: SEP 2010 |
| ISSN: | 1678-8060 0074-0276 |
| Popis: | There is a little-noticed trend involving human immunodeficiency virus (HIV)-infected patients suspected of having tuberculosis: the triple-treatment regimen recommended in Brazil for years has been potentially ineffective in over 30% of the cases. This proportion may be attributable to drug resistance (to at least 1 drug) and/or to infection with non-tuberculous mycobacteria. This evidence was not disclosed in official statistics, but arose from a systematic review of a few regional studies in which the diagnosis was reliably confirmed by mycobacterial culture. This paper clarifies that there has long been ample evidence for the potential benefits of a four-drug regimen for co-infected patients in Brazil and it reinforces the need for determining the species and drug susceptibility in all positive cultures from HIV-positive patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|