Transoral fundoplication offers durable symptom control for chronic GERD: 3-year report from the TEMPO randomized trial with a crossover arm

Autor:	Mamoon Raza, Peter G. Mavrelis, Jeffrey A. Heise, Ahmad B. Shughoury, William E. Barnes, Gilbert Simoni, Mark A. Fox, Karim S. Trad
Jazyk:	angličtina
Rok vydání:	2016
Předmět:	Adult Male medicine.medical_specialty Randomization Time Factors Fundoplication Gastroenterology Article law.invention Hiatal hernia 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Heartburn law Internal medicine Transoral fundoplication medicine Humans Esophagitis Peptic Aged Cross-Over Studies business.industry Proton Pump Inhibitors GERD Regurgitation Middle Aged medicine.disease TIF Discontinuation Atypical symptoms Hernia Hiatal Treatment Outcome 030220 oncology & carcinogenesis Chronic Disease Gastroesophageal Reflux Quality of Life 030211 gastroenterology & hepatology Surgery Female medicine.symptom business Esophagitis Abdominal surgery
Zdroj:	Surgical Endoscopy
ISSN:	1432-2218 0930-2794
Popis:	Background Four randomized controlled trials have demonstrated the short-term efficacy and safety of transoral esophagogastric fundoplication (TF) performed with the EsophyX® device in eliminating troublesome gastroesophageal reflux disease (GERD) symptoms in well-selected patient populations. The aim of this study was to assess the durability of these outcomes at 3 years post-procedure. Methods The TF EsophyX versus Medical PPI Open Label trial was conducted in seven US sites. Between June and August 2012, we enrolled patients with small (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148866d77f2ef5f3f32aaa608b4d9314 http://europepmc.org/articles/PMC5443856 Zobrazit plný text záznamu Full text from SpringerLink