Histopathological characterization of the oral lichenoid disease subtypes and the relation with the clinical data
| Autor: | Javier Alberdi-Navarro, Lartitegui-Sebastián Mj, José-Manuel Aguirre-Urizar, Gainza-Cirauqui Ml, Xabier Marichalar-Mendia, Echebarria-Goikouria Ma |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Epithelial dysplasia Pathology medicine.medical_specialty Precancerous conditions Hyperkeratosis Oral medicine Lesion 03 medical and health sciences 0302 clinical medicine Histology Pathological Biopsy Oral and maxillofacial pathology Carcinoma Medicine Humans General Dentistry Aged Retrospective Studies Aged 80 and over Oral Medicine and Pathology medicine.diagnostic_test business.industry Research Mouth -- Diseases -- Diagnosis Retrospective cohort study 030206 dentistry Middle Aged medicine.disease CIENCIAS MÉDICAS [UNESCO] stomatognathic diseases Otorhinolaryngology 030220 oncology & carcinogenesis Dentistry UNESCO::CIENCIAS MÉDICAS Surgery Female Differential diagnosis medicine.symptom business Lichen Planus Oral |
| Zdroj: | Alberdi Navarro, Javier ; Marichalar Mendia, Xabier ; Lartitegui Sebastián, María José ; Gainza Cirauqui, María Luisa ; Echebarria Goicouria, María Ángeles ; Aguirre Urízar, José Manuel. Histopathological characterization of the oral lichenoid disease subtypes and the relation with the clinical data. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 22 3 2017: 8 Medicina Oral, Patología Oral y Cirugía Bucal RODERIC. Repositorio Institucional de la Universitat de Valéncia instname |
| Popis: | Background: The aim of the study was to analyze the histopathological characteristics of samples with a diagnosis of oral lichenoid disease (OLD) and their link with the location and the type of clinical lesion, and the clinicopathological subtypes. Material and methods: Retrospective study on 85 consecutive patients diagnosed with OLD (58 women and 27 men, mean age of 57.7 years). Clinical and histopathological characterization of each case (modified WHO criteria). Collection of the clinical and histopathological data of the lesions. Descriptive and comparative statistical analysis of the results. Results: The 78.8% of the cases were considered clinically typical while the 21.2% were considered compatible. Histologically, 52.9% were classified as typical and 47.1% as compatible. Biopsies from "plaque-like" lesions presented hyperkeratosis (p>0.001) and epithelial dysplasia (p=0.06) more frequently. Furthermore, acute inflammation was more evident in erosive-ulcerative lesions (p=0.001). Differences regarding the location of the biopsy were statistically non-significant. However, 42.9% of the tongue biopsies showed epithelial dysplasia. Conclusions: The histopathological aspect of this disorder is not specific and does not allow us to differentiate between the main subtypes. Therefore, the main reasons to perform a biopsy in this disorder are to define the differential diagnosis and to rule out epithelial dysplasia or a carcinoma. The final histopathological result may be subject to the type of lesion that is biopsied. peer-reviewed |
| Databáze: | OpenAIRE |
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