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Background: The autologous fat grafting is commonly used for reconstructive or aesthetic purpose. However, due to the huge variation in methods, its retention rate varies a lot. External Volume Expansion (EVE) has been used to treat recipient sites of fat grafting. Concerns have raised regarding its effectiveness and safety. Methods: We have searched the PubMed, EMBASE, and the Cochrane Library for studies on EVE-assisted fat grafting published from 2000 to 2020. A meta-analysis was conducted to pool the retention rate. The incidence of complications was assessed for reconstructive or aesthetic purpose. Results: The 11 included studies involved 1152 patients with operations on 1794 breasts. Four studies were included in the meta-analysis. The pooled retention rate was 65% (95%CI 49-79). Eight studies reported the complications. The total complication incidence was 34%, which is 35% for aesthetic group and 33% for reconstructive group. The complication rate was not obviously different between two groups. Conclusions: The study demonstrates that the EVE-assisted fat grafting has better retention rate than traditional fat grafting. However, the data showed that the complication rate was much higher in the EVE-assisted group. Level of Evidence: The author assigned a level of evidence to each article according to Oxford Center for Evidence-based medicine guidelines. Six studies were level Ⅲ and five studies were level Ⅳ. |
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