A pyoderma gangrenous-like cutaneous leishmaniasis in a Libyan woman with rheumatoid arthritis: a case report
| Autor: | Said El-zubi, Omar Hamarsheh, Ali El-Zurghany, Aisha Gashout, Hamida Al-Dwibe, Ahmad Amro, Mohamed El-Hashme, Mokhtar Maree |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Sodium stibogluconate 030231 tropical medicine Pyoderma lcsh:Medicine Leishmaniasis Cutaneous Case Report Libya General Biochemistry Genetics and Molecular Biology Arthritis Rheumatoid 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Cutaneous leishmaniasis Medicine Humans Rheumatoid arthritis lcsh:Science (General) skin and connective tissue diseases Pyoderma gangrenous lcsh:QH301-705.5 Leishmania medicine.diagnostic_test business.industry lcsh:R Leishmaniasis General Medicine Middle Aged medicine.disease Dermatology Pyoderma Gangrenosum lcsh:Biology (General) Skin biopsy Pathergy Female business Pyoderma gangrenosum medicine.drug lcsh:Q1-390 |
| Zdroj: | BMC Research Notes BMC Research Notes, Vol 11, Iss 1, Pp 1-4 (2018) |
| ISSN: | 1756-0500 |
| Popis: | Background Several case reports describe diseases presenting with skin ulcerations, which resemble pyoderma gangrenosum especially in immune-compromised patients, often proven on further workup, to have an infective or malignant etiology. However, treatment of pyoderma gangrenosum by systemic steroids or other immunosuppressive agents may worsen the condition. Case presentation We report here, a 45 year-old Libyan woman with rheumatoid arthritis on low dose steroids with pyoderma gangrenosum-like skin lesions and positive pathergy. Slit–smear was positive for Leishmania amastigotes and histopathological examination confirmed the diagnosis of cutaneous leishmaniasis. The lesions healed completely by parenteral sodium stibogluconate (Pentostam) 600 mg daily. Conclusion We report for the first time, a rare and unusual presentation of pyoderma gangrenosum like-cutaneous leishmaniasis in a patient with rheumatoid arthritis. Atypical cutaneous leishmaniasis should not be ruled out in the differential diagnosis of unresponsive skin diseases, with slit/smear and a skin biopsy is required. Electronic supplementary material The online version of this article (10.1186/s13104-018-3272-2) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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