Effect of Iodoacetate Addition to Blood on the Concentration of Plasma Free Amino Acids
| Autor: | Mara E. Markovs, Walter D. Block, Betty F. Steele |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Adult
chemistry.chemical_classification Taurine Methionine biology Cystine Iodoacetates Metabolism In Vitro Techniques Cystathionine beta synthase General Biochemistry Genetics and Molecular Biology Amino acid chemistry.chemical_compound chemistry Biochemistry Blood plasma Methods biology.protein Humans Cysteine Amino Acids |
| Zdroj: | Experimental Biology and Medicine. 128:731-733 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-128-33111 |
| Popis: | SummaryThe oxidizing agent, iodoacetate, used to stabilize cysteine in blood and urine had an adverse effect on the absolute amounts of the S-containing amino acids in blood plasma, in both in vitro and in vivo studies. Methionine concentrations were decreased, while taurine, methionine sulfoxides, cystathionine, and cystine increased over those of the nontreated control samples. The use of the qualitative relationship among methionine and its catabolites, however, seemed to be valid for the in vivo investigation of the metabolism of these amino acids. |
| Databáze: | OpenAIRE |
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