Validation of Addenbrooke's cognitive examination III for detecting mild cognitive impairment and dementia in Japan
Autor: | Megumi Yamaguchi, Nao Imai, Osamu Yokota, Hidenori Yoshida, Norihito Yamada, Tomoko Miki, Seishi Terada, Makiko Horiuchi, Shintaro Takenoshita, Mayumi Yabe |
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Rok vydání: | 2018 |
Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Early detection lcsh:Geriatrics Audiology behavioral disciplines and activities 03 medical and health sciences 0302 clinical medicine Japan mental disorders medicine Disease Exacerbation Dementia Humans Cognitive Dysfunction 030212 general & internal medicine Cognitive impairment Cognitive screening Diagnosis mild cognitive impairment Aged Aged 80 and over Rehabilitation business.industry Addenbrooke’s cognitive examination Reproducibility of Results Mild cognitive impairment Cognition Translating Diagnosis dementia medicine.disease Addenbrooke's cognitive examination Mental Status and Dementia Tests Cognitive test lcsh:RC952-954.6 Early Diagnosis Female Geriatrics and Gerontology business 030217 neurology & neurosurgery Research Article |
Zdroj: | BMC Geriatrics BMC Geriatrics, Vol 19, Iss 1, Pp 1-8 (2019) |
ISSN: | 1471-2318 |
Popis: | BACKGROUND:Early detection of mild cognitive impairment (MCI) and dementia is very important to begin appropriate treatment promptly and to prevent disease exacerbation. We investigated the screening accuracy of the Japanese version of Addenbrooke's Cognitive Examination III (ACE-III) to diagnose MCI and dementia. METHODS:The original ACE-III was translated and adapted to Japanese. It was then administered to a Japanese population. The Hasegawa Dementia Scale-revised (HDS-R) and Mini-mental State Examination (MMSE) were also applied to evaluate cognitive dysfunction. In total, 389 subjects (dementia = 178, MCI = 137, controls = 73) took part in our study. RESULTS:The optimal ACE-III cut-off scores to detect MCI and dementia were 88/89 (sensitivity 0.77, specificity 0.92) and 75/76 (sensitivity 0.82, specificity 0.90), respectively. ACE-III was superior to HDS-R and MMSE in the detection of MCI or dementia. The internal consistency, test-retest reliability, and inter-rater reliability of ACE-III were excellent. CONCLUSIONS:ACE-III is a useful cognitive test to detect MCI and dementia. ACE-III may be widely useful in clinical practice. |
Databáze: | OpenAIRE |
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