Validation of Addenbrooke's cognitive examination III for detecting mild cognitive impairment and dementia in Japan

Autor: Megumi Yamaguchi, Nao Imai, Osamu Yokota, Hidenori Yoshida, Norihito Yamada, Tomoko Miki, Seishi Terada, Makiko Horiuchi, Shintaro Takenoshita, Mayumi Yabe
Rok vydání: 2018
Předmět:
Male
medicine.medical_specialty
medicine.medical_treatment
Early detection
lcsh:Geriatrics
Audiology
behavioral disciplines and activities
03 medical and health sciences
0302 clinical medicine
Japan
mental disorders
medicine
Disease Exacerbation
Dementia
Humans
Cognitive Dysfunction
030212 general & internal medicine
Cognitive impairment
Cognitive screening
Diagnosis mild cognitive impairment
Aged
Aged
80 and over
Rehabilitation
business.industry
Addenbrooke’s cognitive examination
Reproducibility of Results
Mild cognitive impairment
Cognition
Translating
Diagnosis dementia
medicine.disease
Addenbrooke's cognitive examination
Mental Status and Dementia Tests
Cognitive test
lcsh:RC952-954.6
Early Diagnosis
Female
Geriatrics and Gerontology
business
030217 neurology & neurosurgery
Research Article
Zdroj: BMC Geriatrics
BMC Geriatrics, Vol 19, Iss 1, Pp 1-8 (2019)
ISSN: 1471-2318
Popis: BACKGROUND:Early detection of mild cognitive impairment (MCI) and dementia is very important to begin appropriate treatment promptly and to prevent disease exacerbation. We investigated the screening accuracy of the Japanese version of Addenbrooke's Cognitive Examination III (ACE-III) to diagnose MCI and dementia. METHODS:The original ACE-III was translated and adapted to Japanese. It was then administered to a Japanese population. The Hasegawa Dementia Scale-revised (HDS-R) and Mini-mental State Examination (MMSE) were also applied to evaluate cognitive dysfunction. In total, 389 subjects (dementia = 178, MCI = 137, controls = 73) took part in our study. RESULTS:The optimal ACE-III cut-off scores to detect MCI and dementia were 88/89 (sensitivity 0.77, specificity 0.92) and 75/76 (sensitivity 0.82, specificity 0.90), respectively. ACE-III was superior to HDS-R and MMSE in the detection of MCI or dementia. The internal consistency, test-retest reliability, and inter-rater reliability of ACE-III were excellent. CONCLUSIONS:ACE-III is a useful cognitive test to detect MCI and dementia. ACE-III may be widely useful in clinical practice.
Databáze: OpenAIRE
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