Aggressive cutaneous squamous cell carcinoma of the head and neck in patients with chronic lymphocytic leukaemia
Autor: | B. E. J. Hartley, J. M. Henk, Peter Rhys-Evans, Adam Searle, N. M. Breach |
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Rok vydání: | 1996 |
Předmět: |
Male
Oncology medicine.medical_specialty Pathology Skin Neoplasms Chronic lymphocytic leukemia Cell Internal medicine Carcinoma medicine Humans Head and neck Lymph node Aged Aged 80 and over Lymphocytic leukaemia business.industry Incidence (epidemiology) Neoplasms Second Primary General Medicine medicine.disease Leukemia Lymphocytic Chronic B-Cell medicine.anatomical_structure Otorhinolaryngology Epidermoid carcinoma Lymphatic Metastasis Carcinoma Squamous Cell Neoplasm Recurrence Local business |
Zdroj: | The Journal of Laryngology & Otology. 110:694-695 |
ISSN: | 1748-5460 0022-2151 |
DOI: | 10.1017/s0022215100134668 |
Popis: | We describe multiple cutaneous squamous cell carcinomas of the head and neck in five patients with chronic lymphocytic leukaemia (CLL). When associated with CLL, cutaneous squamous cell carcinomata behave in a much more aggressive manner than otherwise expected. Four patients developed local recurrence after primary treatment. All five patients developed lymph node metastases containing squamous cell carcinoma. Three of five patients (60 per cent) had multiple primary lesions.Whereas the increased incidence of second cancers in CLL and notably of skin cancers is documented, little has been written to describe the aggressive behaviour of these tumours. It is important, when treating these patients, to be aware of the high tendency towards local recurrence and lymph node metastasis and to consider an aggressive management plan and careful follow-up. |
Databáze: | OpenAIRE |
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