Evaluation of sialic acid levels in patients with hydatidiform mole: a preliminary study
| Autor: | Hüseyin Çağlayan Özcan, Ebru Öztürk, Irfan Kutlar, Binnur Erbağcı, Seyhun Sucu, Ozcan Balat, Mete Gurol Ugur |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty 030226 pharmacology & pharmacy Gastroenterology Sialic Acid 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Pregnancy Internal medicine Mole Medicine In patient business.industry Significant difference Case-control study Obstetrics and Gynecology Hydatidiform Mole medicine.disease Sialic acid 030104 developmental biology Reproductive Medicine chemistry Biochemistry Gestation business N-Acetylneuraminic acid |
| Zdroj: | Clinical and Experimental Obstetrics & Gynecology. 43:414-416 |
| ISSN: | 0390-6663 |
| DOI: | 10.12891/ceog2156.2016 |
| Popis: | WOS: 000376471700022 PubMed ID: 27328503 Purpose of investigation: This study aims to investigate whether hydatidiform mole (HM) disease with malignant potential is significantly associated with increased sialic acid (SA) levels. Materials and Methods: A total of 114 women were enrolled in this study. Patients were divided into three groups including HM (Group 1, n=34), control group including non-pregnant healthy patients (Group 2, n=42), and another control group including healthy pregnant patients within 12 weeks of gestation (Group 3, n=38). Serum-free SA levels were measured. Results: There was a statistically significant difference in serum-free SA levels among the groups (p < 0.001). Patients with HM had significantly higher levels compared to the control groups. Conclusion: The present study results showed that there was a significant correlation between HM and serum SA level. project research unit of Gaziantep University [TF. 09. 21] This study was granted by the project research unit of Gaziantep University (project number TF. 09. 21) Project research unit of Gaziantep University |
| Databáze: | OpenAIRE |
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