Reprotoxic effects of fenpropimorph on the fertilizing potential of AI boars: A case study
| Autor: | Markus Jung, David Schröter, Martin Schulze, Claus Leiding, B. Hensel, Matthias Lautner |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Germinal epithelium endocrine system BOAR Swine Morpholines medicine.medical_treatment Biology Teratozoospermia Asthenozoospermia chemistry.chemical_compound Endocrinology Animal science Semen medicine Animals Spermatogenesis Insemination Artificial Azoospermia Fenpropimorph urogenital system Artificial insemination medicine.disease Spermatozoa Semen Analysis chemistry Animal Science and Zoology Biotechnology |
| Zdroj: | Reproduction in Domestic Animals. 57:337-340 |
| ISSN: | 1439-0531 0936-6768 |
| DOI: | 10.1111/rda.14062 |
| Popis: | This case study describes the effects of a contamination of boar bedding material with reprotoxic compounds in an AI centre in southern Germany. The origin of the investigations was an extreme decline in the production output of the boars. In July 2021, more than 54% of boars were not in production and over 45% of ejaculates had insufficient sperm quality and quantity, which is a significant drop in comparison with the other months. This drop was accompanied by oligozoospermia (azoospermia), asthenozoospermia and teratozoospermia. Through intensive troubleshooting, the changes could be attributed to fenpropimorph, an ergosterol biosynthesis-inhibiting fungicide with reprotoxic potential, which was found in the sawdust used as bedding as well as in liver samples of affected animals, reaching a concentration (mean ± SD) between 0.20 ± 0.36 mg/kg and 0.019 ± 0.001 mg/kg respectively. Furthermore, autopsy findings revealed hyperaemia of the testis, histologically focal degeneration of the germinal epithelium and signs of reduced spermatogenesis and spermiogenesis. |
| Databáze: | OpenAIRE |
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