Leukoencephalopathy with swelling in children and adolescents: MRI patterns and differential diagnosis
| Autor: | L.M.E. Smit, Peter G. Barth, M.S. van der Knaap, P. Tortori Donati, J. Valk, B.G.M. van Engelen |
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| Přispěvatelé: | Pediatric surgery, Amsterdam Neuroscience - Cellular & Molecular Mechanisms |
| Rok vydání: | 1995 |
| Předmět: |
Male
medicine.medical_specialty Pathology Neurology Adolescent Brain Edema Nerve Fibers Myelinated Prion Diseases Central nervous system disease Leukoencephalopathy White matter medicine Humans Radiology Nuclear Medicine and imaging Child Dominance Cerebral Neuroradiology Cerebral Cortex Neurologic Examination medicine.diagnostic_test business.industry Brain Diseases Metabolic Cysts Infant Newborn Leukoencephalopathy Progressive Multifocal Brain Infant Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Child Preschool Female Neurology (clinical) Neurosurgery Differential diagnosis Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | van der Knaap, M S, Valk, J, Barth, P G, Smit, L M E, van Engelen, B G M & Donati, P T 1995, ' Leukoencephalopathy with swelling in children and adolescents : MRI patterns and differential diagnosis ', Neuroradiology, vol. 37, no. 8, pp. 679-686 . https://doi.org/10.1007/BF00593394 Neuroradiology, 37(8), 679-686. Springer Verlag |
| ISSN: | 0028-3940 |
| DOI: | 10.1007/BF00593394 |
| Popis: | In children, several neurological disorders are characterised by spongiform leukoencephalopathy. MRI of the brain typically shows white matter swelling, but does not enable differentiation of the various underlying disorders. The aim of this article is optimisation of the diagnostic value of MRI in leukoencephalopathy accompanied by swelling. MRI-based inclusion criteria were met by 20 patients in our database. The images were analysed using a detailed scoring list. In 13 of the 20 patients the clinical diagnosis was known (11 definite and 2 probable diagnoses). Characteristic MRI abnormalities could be defined in these patients. Of the 7 patients without a diagnosis, 5 had identical MRI abnormalities: difuse hemisphere swelling and typical cysts in frontoparietal subcortical white matter and the tips of the temporal lobes. The clinical picture was also similar in these patients, suggesting a similar disease. |
| Databáze: | OpenAIRE |
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