Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review
| Autor: | Ana Nunes, Pedro Modas Daniel, João Vieira Branco, Joana Santos Cardoso, Carla Amaro, Diogo Alpuim Costa, Isabel Rosa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Radiation proctitis medicine.medical_treatment Oxigenoterapia Hiperbárica Therapeutic algorithm Radiation proctopathy Review Late radiation tissue injury Proctite Hyperbaric oxygen Neoplasms Hyperbaric oxygen therapy medicine Humans Proctitis Prospective Studies Lesões por Radiação Intensive care medicine Radiation Injuries Radio-induced lesion Hyperbaric Oxygenation Radiotherapy business.industry Delayed radiation injury Multimodality Treatment Gastroenterology Minireviews General Medicine medicine.disease Conservative treatment Clinical Practice Radiation therapy Natural history Oxigenação Hiperbárica business Late sequelae |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação instacron:RCAAP World Journal of Gastroenterology |
| Popis: | Radiotherapy (RT) is the backbone of multimodality treatment of more than half of cancer cases. Despite new modern RT techniques, late complications may occur such as radiation proctitis (RP). The natural history of RP is unpredictable. Minor symptoms may resolve spontaneously or require conservative treatment. On the other hand, for similar and uncomplicated clinical contexts, symptoms may persist and can even be refractory to the progressive increase in treatment measures. Over the last decades, an enormous therapeutic armamentarium has been considered in RP, including hyperbaric oxygen therapy (HBOT). Currently, the evidence regarding the impact of HBOT on RP and its benefits is conflicting. Additional prospective and randomised studies are necessary to validate HBOT's effectiveness in the 'real world' clinical practice. This article reviewed the relevant literature on pathophysiology, clinical presentation, different classifications and discuss RP management including a proposal for a therapeutic algorithm with a focus on HBOT. info:eu-repo/semantics/publishedVersion |
| Databáze: | OpenAIRE |
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