Polymorphonuclear leukocyte function in newborn infants
| Autor: | Frank H. Morriss, Joan W. Stoerner, Eugene W. Adcock, Larry K. Pickering |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Blood Bactericidal Activity
Staphylococcus aureus Oxidative phosphorylation Pentose phosphate pathway medicine.disease_cause Streptococcus agalactiae Microbiology chemistry.chemical_compound Oxygen Consumption Phagocytosis Sepsis Streptococcal Infections Leukocytes Humans Medicine Meningitis Hexosephosphates Hydrogen peroxide Escherichia coli Escherichia coli Infections Polymorphonuclear leukocyte Pentosephosphates biology business.industry Infant Newborn Staphylococcal Infections biology.organism_classification chemistry Pediatrics Perinatology and Child Health business Bacteria Function (biology) |
| Zdroj: | The Journal of Pediatrics. 93:862-864 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/s0022-3476(78)81102-0 |
| Popis: | PHAGOCVTOSIS and killing of bacteria by human polymorphonuclear leukocytes is accompanied by a number of oxidative alterations, including increases in hexose monophosphate shunt activity, oxygen consumption, and hydrogen peroxide production. I The purposes of this study were (1) to investigate H MPS activity in resting and phagocytizing PMNL obtained from infected and healthy infants, (2) to determine the bactericidal activity of PMNL obtained from healthy control infants and adults in the presence of either adult or infant serum, using Staphylococcus aureus and Escherichia coli as the test organisms, and (3) to compare bactericidal activity with HMPS activity in healthy control infants and adults. |
| Databáze: | OpenAIRE |
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